1. Structure
Attention: an error message may appear when using the "paste" option, especially for long sequences. Please try to use the "upload" option.
Enter the PDB file:
Input the chain ID in the PDB file:
Choose 3D window size : Angstrom
2. Sequences
Enter the 1st coding sequence file (fasta format):
Or paste the 1st coding sequence below:
Enter the 2nd coding sequence file (fasta format):
Or paste the 2nd coding sequence below:
Choose the genetic code: These codes correspond to the translation_tables in GENBANK. 0:The Standard Code 1:The Vertebrate Mitochondrial Code 2:The Yeast Mitochondrial Code 3:The Mold, Protozoan, and Coelenterate Mitochondrial Code and the Mycoplasma/Spiroplasma Code 4: The Invertebrate Mitochondrial Code 5: The Ciliate, Dasycladacean and Hexamita Nuclear Code 6: The Echinoderm and Flatworm Mitochondrial Code 7: The Euplotid Nuclear Code 8: The Alternative Yeast Nuclear Code 9: The Ascidian Mitochondrial Code 10: Blepharisma Nuclear Code
Advanced Option :
Positive Selection: dN/dS > Negative Selection: dN/dS < Neutral Evolution : dN/dS in the middle range
Waring: 1. In order to view results in 3D, Chime plug-in has to be installed in your computer.
2. The symbols other than A, T, U, G and C (or a, t, u, g and c) should be removed from the sequences before submitting. More importantly, the sequences should be in the correct reading frames.
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If you have any questions about this websever, please email Han Liang at the University of Chicago.